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Case Reports
. 2013 Nov;42(11):1627-31.
doi: 10.1007/s00256-013-1653-0. Epub 2013 Jun 11.

Perineural spread of cervical cancer to the sciatic nerve

Benjamin Matthew Howe  1 , Kimberly K Amrami, Mark A Nathan, Joaquin J Garcia, Robert J Spinner
Affiliations
Case Reports

Perineural spread of cervical cancer to the sciatic nerve

Benjamin Matthew Howe et al. Skeletal Radiol. 2013 Nov.

Abstract

In this report we present a patient with a recent diagnosis of cervical adenocarcinoma with progressive left lower extremity pain and weakness. MR imaging of the pelvis and subsequent FDG CT/PET were complementary in demonstrating abnormalities worrisome for perineural spread of malignancy, which was confirmed with an open fascicular biopsy of the sciatic nerve. We review the imaging and propose a mechanism of perineural spread to the sciatic nerve, which we believe is supported by the imaging in this case.

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