Obstructive jaundice at the initial presentation in small-cell lung cancer
- PMID: 23754881
- PMCID: PMC3658212
- DOI: 10.2147/imcrj.s8093
Obstructive jaundice at the initial presentation in small-cell lung cancer
Abstract
Obstructive jaundice sometimes may develop in association with advanced small-cell lung cancer (SCLC); however, SCLC initially presenting with obstructive jaundice is rare. This report presents the cases of two SCLC patients with obstructive jaundice at the initial diagnosis. A 64-year-old male presented with obstructive jaundice due to a tumor at the head of the pancreas. He was diagnosed with SCLC by transbronchial biopsy from a lung tumor in the left upper lobe. Another 74-year-old male was admitted with jaundice due to a tumor in the porta hepatis. He was also diagnosed with SCLC by a fine-needle aspiration biopsy of a lung tumor in the left lower lobe. Both cases were successfully treated with systemic chemotherapy after endoscopic retrograde biliary drainage.
Keywords: biliary obstruction; jaundice; metastasis; small-cell lung carcinoma.
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References
-
- Govindan R, Page N, Morgensztern D, et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database. J Clin Oncol. 2006;24:4539–4544. - PubMed
-
- Lokich JJ, Kane RA, Harrison DA, McDermott WV. Biliary tract obstruction secondary to cancer: management guidelines and selected literature review. J Clin Oncol. 1987;5:969–981. - PubMed
-
- Maeno T, Satoh H, Ishikawa H, et al. Patterns of pancreatic metastasis from lung cancer. Anticancer Res. 1998;18:2881–2884. - PubMed
-
- Matsukuma S, Suda K, Abe H, Ogata S, Wada R. Metastatic cancer involving pancreatic duct epithelium and its mimicry of primary pancreatic cancer. Histopathology. 1997;30:208–213. - PubMed
-
- Dunkerley RC, Dunn GD. Use of retrograde cholangiography in guiding radiotherapy of obstructive jaundice due to tumor. Am J Gastroenterol. 1976;66:283–286. - PubMed
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