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. 2012 Oct 25:5:73-7.
doi: 10.2147/IMCRJ.S35818. Print 2012.

Collision tumors in the gastrointestinal tract: a rare case series

Affiliations

Collision tumors in the gastrointestinal tract: a rare case series

Aruna Bhattacharya et al. Int Med Case Rep J. .

Abstract

A collision tumor is one where histology shows the presence of two distinct primaries involving the same organ without intermixture of individual cell types, ie, a side by side pattern. Here we present three rare cases of collision tumors involving the stomach and transverse colon. There were two cases of collision tumors involving the stomach, one of which was a combination of adenocarcinoma and low-grade non-Hodgkin's (mucosa-associated lymphoid tissue) lymphoma, and the other showed the presence of non-Hodgkin's lymphoma involving the entire stomach wall along with adenocarcinoma infiltrating the muscle layer. The third case comprised a mucinous adenocarcinoma and carcinoid tumor in the large gut.

Keywords: collision tumor; gastrointestinal tract; histology.

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Figures

Figure 1
Figure 1
Case 1: Adenocarcinoma and lymphomatous portion (hematoxylin and eosin staining, high power).
Figure 2
Figure 2
Case 1: Adenocarcinomatous portion showing cytokeratin positivity.
Figure 3
Figure 3
Case 1: CD20 positivity shown by lymphomatous portion.
Figure 4
Figure 4
Case 2: Adenocarcinoma with lymphoma.
Figure 5
Figure 5
Case 2: Lymphoid portion of the tumor showing CD20 positivity.
Figure 6
Figure 6
Case 3: Carcinoid and adenocarcinomatous portion (hematoxylin and eosin staining, high power).
Figure 7
Figure 7
Case 3: Chromogranin positivity of carcinoid portion.

References

    1. Czerniak A, Lotan G, Engelberg IS, et al. The simultaneous coexistence of adenocarcinoma and primary malignant lymphoma in the stomach. J Surg Oncol. 1985;30:42–45. - PubMed
    1. Kasahara Y, Takemoto M, Morishita A, Kuyama T, Takahashi M, Tanji K. Coexisting adenocarcinoma and malignant lymphoma of the stomach: case report and review of the Japanese literature. Am J Gastroenterol. 1988;83:190–193. - PubMed
    1. Wotherspoon AC, Isaacson PG. Synchronous adenocarcinoma and low grade B-cell lymphoma of mucosa associated lymphoid tissue (MALT) of the stomach. Histopathology. 1995;27:325–331. - PubMed
    1. Adachi Y, Mori M, Enjoji M, Saku M. Coexistence of pseudolymphoma and early carcinoma in the stomach. Arch Pathol Lab Med. 1986;110:1080–1082. - PubMed
    1. Goteri G, Ranaldi R, Rezai B, Baccarini MG, Bearzi I. Synchronous mucosa-associated lymphoid tissue lymphoma and adenocarcinoma of the stomach. Am J Surg Pathol. 1997;21:505–509. - PubMed