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. 2013 May 28:3:138.
doi: 10.3389/fonc.2013.00138. eCollection 2013.

Peripheral T-cell lymphomas: a review of current approaches and hopes for the future

Alan P Skarbnik  1 , Meher Burki, Barbara Pro
Affiliations

Peripheral T-cell lymphomas: a review of current approaches and hopes for the future

Alan P Skarbnik et al. Front Oncol. .

Abstract

Peripheral T-cell lymphomas (PTCL) are a diverse group of lymphoproliferative disorders, which share a common denominator of overall poor prognosis, with few exceptions. In this article, the authors review current standard of care approaches for the treatment of PTCLs, the role of stem-cell/bone marrow transplantation, and current developments in novel targeted therapies.

Keywords: ALCL; PTCL; alisertib; bortezomib; brentuximab; pralatrexate; romidepsin; zanolimumab.

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References

    1. Beitinjaneh A., Saliba R. M., Okoroji G.-J., Korbling M., Alousi A. M., Popat U., et al. (2011). Autologous and allogeneic stem cell transplantation for T-cell lymphoma: the M.D. Anderson Cancer Center experience. ASH Annual Meeting Abstracts, San Diego, Vol. 118, 4118
    1. Broussais-Guillaumot F., Coso D., Belmecheri N., Ivanov V., de Collela J. M., Aurran-Schleinitz T., et al. (2013). Peripheral T-cell lymphomas: analysis of histology, staging and response to treatment of 208 cases at a single institution. Leuk. Lymphoma [Epub ahead of print]. - PubMed
    1. Coiffier B., Pro B., Prince H. M., Foss F., Sokol L., Greenwood M., et al. (2012). Results from a pivotal, open-label, phase II study of romidepsin in relapsed or refractory peripheral T-cell lymphoma after prior systemic therapy. J. Clin. Oncol. 30, 631–63610.1200/JCO.2011.37.4223 - DOI - PubMed
    1. Corradini P., Tarella C., Zallio F., Dodero A., Zanni M., Valagussa P., et al. (2006). Long-term follow-up of patients with peripheral T-cell lymphomas treated up-front with high-dose chemotherapy followed by autologous stem cell transplantation. Leukemia 20, 1533–153810.1038/sj.leu.2404306 - DOI - PubMed
    1. Cress W. D., Seto E. (2000). Histone deacetylases, transcriptional control, and cancer. J. Cell. Physiol. 184, 1–1610.1002/(SICI)1097-4652(200007)184:1<1::AIDJCP1>3.0.CO;2-7 - DOI - PubMed

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