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. 2013 Sep:89:205-9.
doi: 10.1016/j.fitote.2013.06.005. Epub 2013 Jun 10.

Daphmacromines K-O, alkaloids from Daphniphyllum macropodum

Ming-Ming Cao  1 , Lei Wang, Yu Zhang, Hong-Ping He, Yu-Cheng Gu, Qiang Zhang, Yan Li, Chun-Mao Yuan, Shun-Lin Li, Ying-Tong Di, Xiao-Jiang Hao
Affiliations

Daphmacromines K-O, alkaloids from Daphniphyllum macropodum

Ming-Ming Cao et al. Fitoterapia. 2013 Sep.

Abstract

Five new yuzurimine-type Daphniphyllum alkaloids, daphmacromines K-O (1-5), were isolated from the leaves and stems of Daphniphyllum macropodum. Their structures were elucidated by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry. Daphmacromine O (5) showed moderate cytotoxic activity against brine shrimp.

Keywords: Cytotoxic activity; Daphmacromines K–O; Daphniphyllaceae; Daphniphyllum macropodum.

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