Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2013 Jun 12;17(3):148.
doi: 10.1186/cc12717.

Sepsis after Scotland: enough with the averages, show us the effect modifiers

Theodore J Iwashyna, Andrew J Odden
Comment

Sepsis after Scotland: enough with the averages, show us the effect modifiers

Theodore J Iwashyna et al. Crit Care. .

Abstract

Cuthbertson and colleagues demonstrate that survivors of severe sepsis face, in general continued ongoing high mortality and quite poor quality of life. This cohort caps the initial, problem-definition stage on long-term outcomes after critical illness. Having compellingly demonstrated the opportunities for improvements in outcomes, epidemiologic and behavioral research must now to turn to understanding the mechanisms by which these outcomes can be improved. Such fundamental research will provide the evidence base to drive informed and successful interventional trials.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Disablement process model.
See this image and copyright information in PMC

Comment on

  • Mortality and quality of life in the five years after severe sepsis.
    Cuthbertson BH, Elders A, Hall S, Taylor J, MacLennan G, Mackirdy F, Mackenzie SJ; Scottish Critical Care Trials Group; Scottish Intensive Care Society Audit Group. Cuthbertson BH, et al. Crit Care. 2013 Apr 16;17(2):R70. doi: 10.1186/cc12616. Crit Care. 2013. PMID: 23587132 Free PMC article.

References

    1. Cuthbertson BH, Elders A, Hall S, Taylor J, Maclennan G, McKirdy F, Mackenzie SJ, Scctg And Sics SC. Mortality and quality of life in the five years after severe sepsis. Crit Care. 2013;17:R70. - PMC - PubMed
    1. Cuthberts on BH, Roughton S, Jenkinson D, Maclennan G, Vale L. Quality of life in the five years after intensive care: a cohort study. Crit Care. 2010;14:R6. - PMC - PubMed
    1. Herridge MS, Tansey CM, Matté A, Tomlinson G, Diaz-Granados N, Cooper A, Guest CB, Mazer CD, Mehta S, Stewart TE, Kudlow P, Cook D, Slutsky AS, Cheung AM. Canadian Critical Care Trials Group. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med. 2011;364:1293–1304. - PubMed
    1. Quartin AA, Schein RMH, Kett DH, Peduzzi PN. Magnitude and duration of the effect of sepsis on survival. JAMA. 1997;277:1058–1063. - PubMed
    1. Iwashyna TJ, Cooke CR, Wunsch H, Kahn JM. The population burden of long-term survivorship after severe sepsis among older Americans. J Am Geriatr Soc. 2012;60:1070–1077. - PMC - PubMed

Publication types