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. 2013 Oct;57(7):1001-4.
doi: 10.1093/cid/cit393. Epub 2013 Jun 11.

The serum galactomannan index predicts mortality in hematopoietic stem cell transplant recipients with invasive aspergillosis

Cynthia E Fisher  1 , A Michal Stevens, Wendy Leisenring, Steven A Pergam, Michael Boeckh, Tobias M Hohl
Affiliations

The serum galactomannan index predicts mortality in hematopoietic stem cell transplant recipients with invasive aspergillosis

Cynthia E Fisher et al. Clin Infect Dis. 2013 Oct.

Abstract

We examined the relationship between serum and bronchoalveolar lavage (BAL) galactomannan index (GMI) values and mortality in allogeneic hematopoietic cell transplant recipients with invasive pulmonary aspergillosis. Using a clinical sign and symptom-initiated approach, we found that the serum but not the BAL GMI level correlated with 42- and 180-day patient mortality.

Keywords: Aspergillus; aspergillosis; galactomannan; mortality; transplant.

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Figures

Figure 1.
Figure 1.
Kaplan-Meier survival curves for different serum galactomannan (GM; A) and bronchoalveolar lavage (BAL) GM (B) index cutoffs, and cumulative incidence curves for respiratory-specific mortality for different serum (C) and BAL (D) GM index cutoffs through 180 days post–invasive pulmonary aspergillosis diagnosis. Abbreviations: BAL, bronchoalveolar lavage; CI, cumulative incidence; GM, galactomannan; SGM, serum galactomannan.
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References

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