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. 2013 Jun 14;62(23):463-5.

Update to Interim Guidance for Preexposure Prophylaxis (PrEP) for the Prevention of HIV Infection: PrEP for injecting drug users

Centers for Disease Control and Prevention (CDC)

Update to Interim Guidance for Preexposure Prophylaxis (PrEP) for the Prevention of HIV Infection: PrEP for injecting drug users

Centers for Disease Control and Prevention (CDC). MMWR Morb Mortal Wkly Rep. .

Abstract

On June 12, 2013, the Thailand Ministry of Health and CDC published results from a randomized controlled trial of a daily oral dose of 300 mg of tenofovir disoproxil fumarate (TDF) that showed efficacy in reducing the acquisition of human immunodeficiency virus (HIV) infection among injecting drug users (IDUs) (1). Based on these findings, CDC recommends that preexposure prophylaxis (PrEP) be considered as one of several prevention options for persons at very high risk for HIV acquisition through the injection of illicit drugs.

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References

    1. Choopanya K, Martin M, Suntharasamai P, et al. Antiretroviral prophylaxis for HIV infection among people who inject drugs in Bangkok, Thailand: a randomized, double-blind, placebo-controlled trial. Lancet. 2013 June; In press.
    1. CDC. Estimated HIV incidence in the United States, 2007–2010. HIV surveillance supplemental report. 2012;17(4) Available at http://www.cdc.gov/hiv/topics/surveillance/resources/reports/#supplemental.
    1. CDC. HIV infection and HIV-associated behaviors among injecting drug users—20 cities, United States, 2009. MMWR. 2012;61:133–8. - PubMed
    1. Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363:2587–99. - PMC - PubMed
    1. Baeten JM, Donnell D, Ndase P, et al. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367:399–410. - PMC - PubMed

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