Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jun;13(3):269-74.
doi: 10.7861/clinmedicine.13-3-269.

Gastrointestinal and liver disease in pregnancy

Charlotte J Frise  1 , Catherine Williamson
Affiliations

Gastrointestinal and liver disease in pregnancy

Charlotte J Frise et al. Clin Med (Lond). 2013 Jun.

Abstract

Gastrointestinal (GI) conditions are common in women of childbearing age. They often present before pregnancy but can arise de novo during pregnancy. The physiological changes that occur during pregnancy can influence the differential diagnosis of common GI presentations, affect the interpretation of diagnostic tests and restrict the use of diagnostic or therapeutic procedures. In this article, we summarise the clinical features, investigation and management of common GI and liver conditions that are incidental to pregnancy, and describe the specific features of pregnancy-related disorders that are less frequently encountered by general physicians. Newer developments in areas that are increasingly encountered in obstetric medical practice, including pregnancy after bariatric procedures, are also described.

Keywords: HELLP syndrome; Pregnancy; hyperemesis gravidarum; hypertensive disorders of pregnancy; liver disease; obstetric cholestasis.

PubMed Disclaimer

References

    1. Powrie RO, Greene MF, Camann W, editors. de Swiet’s Medical Disorders in Obstetric Practice. 5th edn. Chichester: Wiley-Blackwell; 2010.
    1. Van der Woude CJ, Kolacek S, Dotan I, et al. European evidenced-based consensus on reproduction in inflammatory bowel disease. J Crohns Colitis. 2010;4:493–510. doi: 10.1016/j.crohns.2010.07.004. - DOI - PubMed
    1. Cantwell R, Clutton-Brock T, Cooper G, et al. Saving mothers’ lives. Reviewing maternal deaths to make motherhood safer: 2006–2008. The eighth report on confidential enquiries into maternal deaths in the United Kingdom. BJOG. 2011;118(suppl 1):1–203. - PubMed
    1. Dao T, Kuhn J, Ehmer D, et al. Pregnancy outcomes after gastric-bypass surgery. Am J Surg. 2006;192:762–6. doi: 10.1016/j.amjsurg.2006.08.041. - DOI - PubMed
    1. Ch’ng CL, Morgan M, Hainsworth I, Kingham JG. Prospective study of liver dysfunction in pregnancy in Southwest Wales. Gut. 2002;51:876–80. - PMC - PubMed

MeSH terms

Supplementary concepts