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. 2013 Aug;51(8):2761-5.
doi: 10.1128/JCM.00802-13. Epub 2013 Jun 12.

Population structure and antimicrobial susceptibility of both nonpersistent and persistent Pseudomonas aeruginosa isolates recovered from cystic fibrosis patients

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Population structure and antimicrobial susceptibility of both nonpersistent and persistent Pseudomonas aeruginosa isolates recovered from cystic fibrosis patients

Ana Fernández-Olmos et al. J Clin Microbiol. 2013 Aug.

Abstract

Seventy-six Pseudomonas aeruginosa isolates recovered from chronically (n=18) and nonchronically (n=18) colonized cystic fibrosis (CF) patients (2002 to 2009) were grouped in separate polyclonal populations. International CF epidemic clones were not identified, but the high-risk clone ST274, also found circulating in Spanish hospitals, was present. Persistent isolates were more resistant to antibiotics than nonpersistent isolates.

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Figures

Fig 1
Fig 1
Minimum spanning tree (MST) of nonpersistent and persistent CF clones compared with international CF clones and multiresistant clones recovered from Spanish hospitals.
Fig 2
Fig 2
Phylogenetic BAPS analysis of the 7 MLST concatenated alleles from nonpersistent and persistent CF clones recovered in our CF unit compared with international CF clones and multiresistant clones recovered from Spanish hospitals.

References

    1. García-Castillo M, del Campo R, Morosini MI, Riera E, Cabot G, Willems R, van Mansfeld R, Oliver A, Cantón R. 2011. Wide dispersion of ST175 clone despite high genetic diversity of carbapenem-nonsusceptible Pseudomonas aeruginosa clinical strains in 16 Spanish hospitals. J. Clin. Microbiol. 49:2905–2910 - PMC - PubMed
    1. Selezska K, Kazmierczak M, Müsken M, Garbe J, Schobert M, Häussler S, Wiehlmann L, Rohde C, Sikorski J. 2012. Pseudomonas aeruginosa population structure revisited under environmental focus: impact of water quality and phage pressure. Environ. Microbiol. 14:1952–1967 - PubMed
    1. Waters V, Zlosnik JE, Yau YC, Speert DP, Aaron SD, Guttman DS. 2012. Comparison of three typing methods for Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Eur. J. Clin. Microbiol. Infect. Dis. 31:3341–3350 - PubMed
    1. Tramper-Stranders GA, van der Ent CK, Molin S, Yang L, Hansen SK, Rau MH, Ciofu O, Johansen HK, Wolfs TF. 2012. Initial Pseudomonas aeruginosa infection in patients with cystic fibrosis: characteristics of eradicated and persistent isolates. Clin. Microbiol. Infect. 18:567–574 - PubMed
    1. van Mansfeld R, Jongerden I, Bootsma M, Buiting A, Bonten M, Willems R. 2010. The population genetics of Pseudomonas aeruginosa isolates from different patient populations exhibits high-level host specificity. PLoS One 5:e13482.10.1371/journal.pone.0013482 - DOI - PMC - PubMed

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