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. 2013:2013:989745.
doi: 10.1155/2013/989745. Epub 2013 May 9.

A Case of QT Prolongation Associated with Panhypopituitarism

Dilek Arpaci  1 , Mustafa Volkan Demir, Tayfun Garip, Ali Tamer
Affiliations

A Case of QT Prolongation Associated with Panhypopituitarism

Dilek Arpaci et al. Case Rep Endocrinol. 2013.

Abstract

We describe a 37-year-old patient with panhypopituitarism who experienced symptoms and signs of hormonal insufficiency and QT prolongation on electrocardiogram without electrolyte disturbances. After hormonal (steroidal and thyroid) replacement therapy electrocardiographic findings were normalized. Hormonal disorders should be considered as a cause of long QT intervals which may lead to torsade de pointes, even if plasma electrolyte levels are normal, because life-threatening arrhythmia is treatable by supplementation of the hormone that is lacking.

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Figures

Figure 1
Figure 1
Twelve-lead electrocardiogram on admission shows long QT intervals and inverted T waves.
Figure 2
Figure 2
Some significant ECG events and minimal heart rate ECG record which were detected at 24-hour rythm holter ECG.
Figure 3
Figure 3
Four weeks after starting steroid and thyroid replacement therapy, twelve-lead electrocardiogram demonstrates normal QT intervals.
See this image and copyright information in PMC

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