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Case Reports
. 2014 Mar;33(1):79-81.
doi: 10.3109/15569527.2013.802696. Epub 2013 Jun 14.

Bilateral diffuse iris atrophy after the use of oral clarithromycin

Paris Tranos  1 , Mayssa B Nasr, Solon Asteriades, Athanasios Vakalis, Ilias Georgalas
Affiliations
Case Reports

Bilateral diffuse iris atrophy after the use of oral clarithromycin

Paris Tranos et al. Cutan Ocul Toxicol. 2014 Mar.

Abstract

Purpose: To report a newly recognised advert event of clarithromycin.

Methods: Retrospective, case report.

Results: A 30-year old female referred to our centre with bilateral diffuse iris atrophy after the use of oral clarithromycin for a pulmonary infection.

Conclusions: Bilateral acute depigmentation of the iris is a new clinical entity. Iris transillumination and sphincter paralysis are recognised adverse effects of oral antibiotic therapy, but to our knowledge no other publication has referred to uveitis-like syndrome due to oral administration of clarithromycin.

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