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. 2013 Jul;19(7):1102-4.
doi: 10.3201/eid1907.130044.

Unique clone of Coxiella burnetii causing severe Q fever, French Guiana

Aba Mahamat  1 , Sophie Edouard, Magalie Demar, Philippe Abboud, Jean-Yves Patrice, Bernard La Scola, Antoine Okandze, Félix Djossou, Didier Raoult
Affiliations

Unique clone of Coxiella burnetii causing severe Q fever, French Guiana

Aba Mahamat et al. Emerg Infect Dis. 2013 Jul.

Abstract

Acute Q fever is an emergent and severe disease in French Guiana. We obtained 5 Coxiella burnetii isolates from samples of patients from Cayenne and found an epidemic clone circulating in Cayenne. This clone has caused pneumonia and endocarditis and seems to be more virulent than previously described strains.

Keywords: Cayenne; Coxiella burnetii; French Guiana; Q fever; bacteria; clone; genotyping; multispacer sequence typing.

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Figures

Figure 1
Figure 1
Immunohistochemical detection of Coxiella burnetii in resected cardiac valve of a 60-year-old man with Q fever endocarditis, Cayenne, French Guiana. Monoclonal antibody against C. burnetii and hematoxylin were used for staining. Original magnification ×50.
Figure 2
Figure 2
Phylogenetic diversity of 34 genotypes of Coxiella burnetii identified by using multispacer sequence typing (MST). Clone from French Guiana isolated in this study is indicated in boldface. Scale bar indicates nucleotide substitutions per site.
See this image and copyright information in PMC

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