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Comment
. 2013 Jun 10;23(6):707-9.
doi: 10.1016/j.ccr.2013.05.013.

Hopping between differentiation states in lung adenocarcinoma

Hideo Watanabe  1 , Matthew Meyerson
Affiliations
Comment

Hopping between differentiation states in lung adenocarcinoma

Hideo Watanabe et al. Cancer Cell. .

Abstract

The work by Cheung and colleagues, in this issue of Cancer Cell, demonstrates another example of how lineage-specific transcriptional regulators of differentiation, GATA6 and HOPX, can control the fate of lung adenocarcinoma progression.

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Figures

Figure 1
Figure 1
Metastatic potential varies among subtypes of lung cancer defined by transcriptional regulation of cell lineages. Transcriptional regulators active in different cell lineages are shaded in green (WNT/TCF), yellow (SOX2), orange (FOXA1), red (NKX2-1) and blue (GATA6/HOPX). Arrows indicate differentiation. Curved arrows indicate malignant transformation.
See this image and copyright information in PMC

Comment on

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