JMML patient-derived iPSCs induce new hypotheses
- PMID: 23766458
- DOI: 10.1182/blood-2013-05-500090
JMML patient-derived iPSCs induce new hypotheses
Abstract
In this issue of Blood, Gandre-Babbe et al have, in part, overcome the obstacle of validating the molecular underpinnings of juvenile myelomonocytic leukemia (JMML) with the generation of induced pluripotent stem cells (iPSCs) from individuals with JMML.
Comment on
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Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia.Blood. 2013 Jun 13;121(24):4925-9. doi: 10.1182/blood-2013-01-478412. Epub 2013 Apr 25. Blood. 2013. PMID: 23620576 Free PMC article. Clinical Trial.
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