Lisinopril-induced angioedema of the lip

Abstract

Angiotensin-converting enzyme (ACE) inhibitors are commonly used in the treatment of hypertension. Angioedema is a known side effect of ACE inhibitors. Awareness of the clinical presentation of angioedema can allow for appropriate medical referral. The case presented here describes a 69-year-old African-American female who presented with a swollen lower lip that had developed overnight. A review of her medical history revealed that she was being treated for hypertension with a combination product containing lisinopril and hydrocholorothiazide. A diagnosis of lisinopril-induced angioedema was made. Her physician was consulted and her medications were discontinued. The lip swelling resolved without incident.