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. 2013 Jun 17;20(7):358-62.
doi: 10.1101/lm.030171.112.

Visual object pattern separation varies in older adults

Heather M Holden  1 , Chelsea Toner, Eva Pirogovsky, C Brock Kirwan, Paul E Gilbert
Affiliations

Visual object pattern separation varies in older adults

Heather M Holden et al. Learn Mem. .

Abstract

Young and nondemented older adults completed a visual object continuous recognition memory task in which some stimuli (lures) were similar but not identical to previously presented objects. The lures were hypothesized to result in increased interference and increased pattern separation demand. To examine variability in object pattern separation deficits, older adults were divided into impaired and unimpaired groups based on performance on a standardized serial list-learning task. Impaired older adults showed intact recognition memory, but were impaired relative to young and unimpaired older adults when identifying similar lure stimuli, demonstrating that object pattern separation varies in older adults.

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Figures

Figure 1.
Figure 1.
Mean proportion of responses (+SE) of new, old, and similar to (A) first presentation of objects (FIRST), (B) repeated presentation of objects (REPEATED), and (C) objects that were similar but not identical to previously presented objects (LURE) for young, older-unimpaired (OU), and older-impaired (OI) adults.
Figure 2.
Figure 2.
Mean difference scores: proportion of “similar” responses to lure stimuli (correct response)–proportion of “old” responses to lure stimuli (false positive response) for young, older-unimpaired (OU), and older-impaired (OI) adults.
See this image and copyright information in PMC

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