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Review
. 2013 Jul;31(4):245-50.
doi: 10.1055/s-0033-1345271. Epub 2013 Jun 17.

Clomiphene citrate in the management of male infertility

Lauren W Roth  1 , Amanda R Ryan, Randall B Meacham
Affiliations
Review

Clomiphene citrate in the management of male infertility

Lauren W Roth et al. Semin Reprod Med. 2013 Jul.

Abstract

Clomiphene citrate, a selective estrogen receptor modulator, has been used to treat infertility in women and men for 50 years. In men, clomiphene citrate has been employed in the management of unexplained infertility, oligo and asthenospermia, hypogonadism, and nonobstructive azoospermia. The available evidence reveals mixed results and suggests that clomiphene citrate may be appropriate for the management of male infertility in specific clinical scenarios. Further research is needed to clarify when clomiphene citrate is indicated in the treatment of male infertility.

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