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. 2013 Jul 22;52(30):7742-6.
doi: 10.1002/anie.201301278. Epub 2013 Jun 14.

Combination of i-motif and G-quadruplex structures within the same strand: formation and application

Jun Zhou  1 , Samir Amrane, Dursun Nizam Korkut, Anne Bourdoncle, Hong-Zhang He, Dik-Lung Ma, Jean-Louis Mergny
Affiliations

Combination of i-motif and G-quadruplex structures within the same strand: formation and application

Jun Zhou et al. Angew Chem Int Ed Engl. .

Abstract

Peaceful coexistence: A double quadruplex composed of an i-motif and a G-quadruplex was constructed within one oligonucleotide strand (see picture). The defined double-quadruplex structure can serve as a NOTIF logic gate on the basis of the fluorescence of crystal violet.

Keywords: G-quadruplexes; circular dichroism; fluorescence; i-motifs; logic gates.

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