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Case Reports
. 2013 Jan;17(1):167-9.
doi: 10.4103/2230-8210.107876.

Hypopituitarism as the presenting feature of bronchogenic carcinoma with metastases to the pituitary gland

Philip C Johnston  1 , Neil R Black, Joe McIlroy, Rose Sharkey, Angela Garvey, John R Lindsay
Affiliations
Case Reports

Hypopituitarism as the presenting feature of bronchogenic carcinoma with metastases to the pituitary gland

Philip C Johnston et al. Indian J Endocrinol Metab. 2013 Jan.

Abstract

Tumours metastasizing to the pituitary gland are uncommon. Symptomatic patients with pituitary metastases can present with diabetes insipidus, headache, visual field defects and/or anterior pituitary hormonal dysfunction. Treatment options for pituitary metastases include, surgical resection, cranial or parasellar irradiation and/or chemotherapy, and hormonal replacement if indicated. The overall prognosis of pituitary metastases is poor. We present a case of hypopituitarism as the presenting feature of bronchogenic carcinoma with metastases to the pituitary gland.

Keywords: Bronchogenic carcinoma; hypopituitarism; pituitary metastases.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
(a) Gadolinium-enhanced brain magnetic resonance imaging (MRI) showing multiple enhancing lesions (white arrows). (b) Gadolinium-enhanced pituitary MRI revealing a mass lesion without evidence of haemorrhage or cystic change, occupying almost all of the pituitary gland (blue arrow), with invasion to the floor of the sella
Figure 2
Figure 2
Computed tomography scan of thorax demonstrating a right hilar mass (red arrow)
See this image and copyright information in PMC

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References

    1. Abrams HL, Spiro R, Goldstein N. Metastases in carcinoma; analysis of 1000 autopsied cases. Cancer. 1950;3:74–85. - PubMed
    1. Chiang MF, Brock M, Patt S. Pituitary metastases. Neurochirurgia (Stuttg) 1990;33:127–31. - PubMed
    1. Sioutos P, Yen V, Arbit E. Pituitary gland metastases. Ann Surg Oncol. 1996;3:94–9. - PubMed
    1. Teears RJ, Silverman EM. Clinicopathologic review of 88 cases of carcinoma metastatic to the putuitary gland. Cancer. 1975;36:216–20. - PubMed
    1. Branch CL Jr, Laws ER., Jr Metastatic tumors of the sella turcica masquerading as primary pituitary tumors. J Clin Endocrinol Metab. 1987;65:469–74. - PubMed

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