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. 2013:2013:604191.
doi: 10.1155/2013/604191. Epub 2013 May 23.

Retinal microvascular abnormalities in neurofibromatosis type 1 associated with congenital retinal macrovessels

Shinji Makino  1 , Katsuhisa Endoh, Hironobu Tampo
Affiliations

Retinal microvascular abnormalities in neurofibromatosis type 1 associated with congenital retinal macrovessels

Shinji Makino et al. Case Rep Ophthalmol Med. 2013.

Abstract

Here, we report a case of retinal microvascular abnormalities in a patient with neurofibromatosis type 1 (NF1) associated with congenital retinal macrovessels. An abnormal retinal macrovessel, crossing the macula horizontally, was detected in the right eye. Additionally, retinal microvascular abnormalities were detected. Eight years after the initial visit, the retinal microvascular abnormalities were noted to have changed substantially. We speculate that retinal microvascular abnormalities in NF1 may change dynamically over the years.

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Figures

Figure 1
Figure 1
Right (a) and left (b) fundus photographs. Note a congenital retinal macrovessel crossing the macula horizontally in the right eye.
Figure 2
Figure 2
High-magnification images of the right fundus. Note dynamic changes to the microvascular abnormality (arrow) (b) in comparison to its appearance at the initial visit (a).
Figure 3
Figure 3
Right (a) and left (b) infrared fundus autofluorescence images. Note multiple bright, patchy lesions in the posterior poles of both eyes. The hyperreflective point at the center of the image is an optical artifact.
See this image and copyright information in PMC

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