Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2013 Jul;15(7):809-10.
doi: 10.1093/neuonc/not095.

Are we ready for a randomized trial of valproic acid in newly diagnosed glioblastoma?

Michael Weller
Editorial

Are we ready for a randomized trial of valproic acid in newly diagnosed glioblastoma?

Michael Weller. Neuro Oncol. 2013 Jul.
No abstract available

PubMed Disclaimer

Comment on

References

    1. Weller M, Stupp R, Wick W. Epilepsy meets cancer: when, why, and what to do about it? Lancet Oncol. 2012;13 e375–e382. - PubMed
    1. Oberndorfer S, Piribauer M, Marosi C, et al. P450 enzyme inducing and non-enzyme inducing antiepileptics in glioblastoma patients treated with standard chemotherapy. J Neurooncol. 2005;72:255–260. - PubMed
    1. Felix FH, Trompieri NM, de Araujo OL, et al. Potential role for valproate in the treatment of high-risk brain tumors of childhood–results from a retrospective observational cohort study. Pediatr Hematol Oncol. 2011;28:556–570. - PubMed
    1. Barker CA, Bishop AJ, Chang M, et al. Valproic acid use during radiation therapy for glioblastoma associated with improved survival. Int J Radiat Oncol Biol Phys. 2013 In press. - PMC - PubMed
    1. Weller M, Gorlia T, Cairncross JG, et al. Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma. Neurology. 2011;77:1156–1164. - PMC - PubMed