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Review
. 2013 Nov-Dec;63(6):374-94.
doi: 10.3322/caac.21195. Epub 2013 Jun 24.

New developments in the diagnosis and treatment of thyroid cancer

Affiliations
Review

New developments in the diagnosis and treatment of thyroid cancer

David F Schneider et al. CA Cancer J Clin. 2013 Nov-Dec.

Abstract

Thyroid cancer exists in several forms. Differentiated thyroid cancers include those with papillary and follicular histologies. These tumors exist along a spectrum of differentiation, and their incidence continues to climb. A number of advances in the diagnosis and treatment of differentiated thyroid cancers now exist. These include molecular diagnostics and more advanced strategies for risk stratification. Medullary cancer arises from the parafollicular cells and not the follicular cells. Therefore, diagnosis and treatment differs from those of differentiated thyroid tumors. Genetic testing and newer adjuvant therapies have changed the diagnosis and treatment of medullary thyroid cancer. This review will focus on the epidemiology, diagnosis, workup, and treatment of both differentiated and medullary thyroid cancers, focusing specifically on newer developments in the field.

Keywords: diagnosis; epidemiology; follicular thyroid cancer; medullary thyroid cancer; papillary thyroid cancer; thyroid cancer; treatment.

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Figures

Figure 1
Figure 1
Classification of Follicular Cell Derived Tumors
Figure 2
Figure 2
Lymph Node Compartments of the Neck

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References

    1. Clark OH. Thyroid cancer and lymph node metastases. J Surg Oncol. 2011;103:615–8. - PubMed
    1. Sippel RS, Chen H. Controversies in the surgical management of newly diagnosed and recurrent/residual thyroid cancer. Thyroid. 2009;19(12):1373–80. - PubMed
    1. Patel KN, Shaha AR. Poorly differentiated and anaplastic thyroid cancer. Cancer Control. 2006;13:119–28. - PubMed
    1. Udelsman R, Chen H. The current management of thyroid cancer. Adv Surg. 1999;33:1–27. - PubMed
    1. Moo-Young TA, Traugott AL, Moley JF. Sporadic and familial medullary thyroid carcinoma: state of the art. Surg Clin North Am. 2009;89(5):1193–204. - PMC - PubMed

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