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. 1990 Jul;70(3):411-3.

In vivo IL-1 potentiates both specific and non-specific arms of immune response to infection

C Cheers  1 , Y F Zhan, P J Egan
Affiliations

In vivo IL-1 potentiates both specific and non-specific arms of immune response to infection

C Cheers et al. Immunology. 1990 Jul.

Abstract

Injection of 10(5) U interleukin-1 (IL-1) 4 hr before intravenous infection with Listeria monocytogenes hastens recovery of mice. This is accompanied not only by early stimulation of colony-forming cells in the spleen to levels higher than those in untreated, infected mice but also by accelerated activation of lymphokine-producing, specific T lymphocytes.

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