Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jun 25:13:608.
doi: 10.1186/1471-2458-13-608.

Aboriginal birth cohort (ABC): a prospective cohort study of early life determinants of adiposity and associated risk factors among Aboriginal people in Canada

Collaborators, Affiliations

Aboriginal birth cohort (ABC): a prospective cohort study of early life determinants of adiposity and associated risk factors among Aboriginal people in Canada

Gita Wahi et al. BMC Public Health. .

Abstract

Background: Aboriginal people living in Canada have a high prevalence of obesity, type 2 diabetes, and cardiovascular disease (CVD). To better understand the pre and postnatal influences on the development of adiposity and related cardio-metabolic factors in adult Aboriginal people, we will recruit and follow prospectively Aboriginal pregnant mothers and their children - the Aboriginal Birth Cohort (ABC) study.

Methods/design: We aim to recruit 300 Aboriginal pregnant mothers and their newborns from the Six Nations Reserve, and follow them prospectively to age 3 years. Key details of environment and health including maternal nutrition, glucose tolerance, physical activity, and weight gain will be collected. At birth, cord blood and placenta samples will be collected, as well as newborn anthropometric measurements. Mothers and offspring will be followed annually with serial measurements of diet and physical activity, growth trajectory, and adiposity.

Discussion: There is an urgent need to understand maternal and child factors that underlie the early development of adiposity and type 2 diabetes in Aboriginal people. The information generated from this cohort will assist the Six Nations community in developing interventions to prevent early adiposity in Aboriginal children.

PubMed Disclaimer

References

    1. Statistics Canada. Ethnocultural portrait of Canada highlight tables, 2006 census. Ottawa: Statistics Canada Catalogue no. 97-562-XWE2006002; 2006. Version updated April 2, 2008. Ottawa. http://www12.statcan.ca/english/census06/data/highlights/ethnic/index.cf... = E (accessed February 27)
    1. Anand SS, Yusuf S, Jacobs R, Davis AD, Yi Q, Gerstein H, Montague PA, Lonn E. Risk factors, atherosclerosis, and cardiovascular disease among Aboriginal people in Canada: the study of health assessment and risk evaluation in Aboriginal peoples (SHARE-AP) Lancet. 2001;358(9288):1147–1153. doi: 10.1016/S0140-6736(01)06255-9. - DOI - PubMed
    1. Amed S, Dean HJ, Panagiotopoulos C, Sellers EA, Hadjiyannakis S, Laubscher TA, Dannenbaum D, Shah BR, Booth GL, Hamilton JK. Type 2 diabetes, medication-induced diabetes, and monogenic diabetes in Canadian children. Diabetes Care. 2010;33(4):786–791. doi: 10.2337/dc09-1013. - DOI - PMC - PubMed
    1. Gluckman PD, Hanson MA, Beedle AS. Early life events and their consequences for later disease: a life history and evolutionary perspective. Am J Hum Biol. 2007;19(1):1–19. doi: 10.1002/ajhb.20590. - DOI - PubMed
    1. Anand SS, Davis AD, Ahmed R, Jacobs R, Xie C, Hill A, Sowden J, Atkinson S, Blimkie C, Brouwers M, Morrison K, de Koning L, Gerstein H, Yusuf S. SHARE-AP ACTION investigators. A family-based intervention to promote healthy lifestyles in an Aboriginal community in Canada. Can J Public Health. 2007;98(6):447–452. - PMC - PubMed

Publication types