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Randomized Controlled Trial
. 2013 Jun 27:14:91.
doi: 10.1186/1471-2296-14-91.

Supporting smoking cessation in chronic obstructive pulmonary disease with behavioral intervention: a randomized controlled trial

Peian Lou  1 , Yanan Zhu, Peipei Chen, Pan Zhang, Jiaxi Yu, Ning Zhang, Na Chen, Lei Zhang, Hongmin Wu, Jing Zhao
Affiliations
Randomized Controlled Trial

Supporting smoking cessation in chronic obstructive pulmonary disease with behavioral intervention: a randomized controlled trial

Peian Lou et al. BMC Fam Pract. .

Abstract

Background: Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD). But a fewer smoking cessation measures were conducted in communities for smokers with COPD in China. The aim of our study was to assess the preventive effects of behavioral interventions for smoking cessation and potential impact factors in smokers with COPD in China.

Methods: In a randomised controlled smoking cessation trial 3562 patients with COPD who were current smoker were allocated to intervention group received behavioral intervention and control group received the usual care for two years. The primary efficacy endpoint was the complete and continuous abstinence from smoking from the beginning of month 24 to the end of month 30. Participants were followed up at month 48.

Results: Continuous smoking abstinence rates from month 24 to 30 were significantly higher in participants receiving behavioral intervention than in those receiving usual care (46.4% vs 3.4%, p < 0.001). Continuous abstinence rates from months 24 to 36 (45.8% vs 4.0%) and months 24 to 48 (44.3% vs 5.1%) were also higher in participants receiving behavioral intervention than in those control group. Family members or family physicians/nurses smoking were first identified to influence smoking cessation.

Conclusions: Behavioral intervention doubled the smoking cessation rate in patients with COPD and was complied well by the general practitioners. The family members and family physicians/nurses smoking were the main risk factors for smoking cessation.

Trial registration: Chinese Clinical Trials Registration (ChiCTR-TRC-12001958).

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Figures

Figure 1
Figure 1
Consort figure of the trial profile.
See this image and copyright information in PMC

References

    1. Celli BR, MacNee W. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J. 2004;23:932–946. doi: 10.1183/09031936.04.00014304. - DOI - PubMed
    1. Hurd S, Pauwels R. Global Initiative for Chronic Obstructive Lung Diseases (GOLD) Pulm Pharmacol Ther. 2002;15:353–355. doi: 10.1006/pupt.2002.0381. - DOI - PubMed
    1. Collishaw NE. The Tobacco Epidemic: A Global Public Health Emergency Tobacco. Geneva: World Health Organization; 1996.
    1. Lokke A, Lange P, Scharling H, Fabricius P, Vestbo J. Developing COPD: a 25 year follow up study of the general population. Thorax. 2006;61:935–939. doi: 10.1136/thx.2006.062802. - DOI - PMC - PubMed
    1. Zhou Y, Wang C, Yao W, Chen P, Kang J, Huang S. et al.COPD in Chinese nonsmokers. Eur Respir J. 2009;33:509–518. doi: 10.1183/09031936.00084408. - DOI - PubMed

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