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. 1990 Jul;28(7):1673-5.
doi: 10.1128/jcm.28.7.1673-1675.1990.

The 83-kilodalton antigen of Borrelia burgdorferi which stimulates immunoglobulin M (IgM) and IgG responses in infected hosts is expressed by a chromosomal gene

R B Lefebvre  1 , G C Perng, R C Johnson
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The 83-kilodalton antigen of Borrelia burgdorferi which stimulates immunoglobulin M (IgM) and IgG responses in infected hosts is expressed by a chromosomal gene

R B Lefebvre et al. J Clin Microbiol. 1990 Jul.

Abstract

We report the cloning and characterization of a chromosomal gene from Borrelia burgdorferi expressing an 83-kilodalton protein antigen in Escherichia coli. The antigen reacted strongly with antisera from two human Lyme disease patients. The chromosomal gene was expressed in a 6.5-kilobase-pair ClaI fragment cloned into a variable-reading-frame plasmid vector.

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References

    1. Science. 1985 Oct 4;230(4721):85-7 - PubMed
    1. J Infect Dis. 1985 Sep;152(3):478-84 - PubMed
    1. J Immunol Methods. 1985 Nov 28;84(1-2):53-63 - PubMed
    1. Nature. 1985 Nov 21-27;318(6043):257-63 - PubMed
    1. Infect Immun. 1986 Oct;54(1):207-12 - PubMed

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