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Review
. 2013 Apr;9(2):69-72.
doi: 10.14797/mdcj-9-2-69.

Endovascular techniques in limb salvage: cutting, cryo, brachy, and drug-eluting balloons

Mark G Davies  1 , Javier E Anaya-Ayala
Affiliations
Review

Endovascular techniques in limb salvage: cutting, cryo, brachy, and drug-eluting balloons

Mark G Davies et al. Methodist Debakey Cardiovasc J. 2013 Apr.

Abstract

The complex pathophysiology response to injury of the lower-extremity arteries has prompted the development of several unique balloon technologies to overcome initial technical failures and short-term intimal hyperplasia. Cryoplasty alters the cellular and mechanical properties of the vessel wall during angioplasty. Cutting balloons incise the wall, preventing elastic recoil and allowing expansion of the lumen at a lower pressure, thus limiting barotrauma. Drug-eluting balloons actively transfer inhibitory compounds to the wall during the initial therapy, while brachytherapy balloons allow for localized delivery of radiation to inhibit the proliferative response seen after angioplasty. These platforms provide unique means to enhance immediate and short-term results and also reduce stent usage in the lower extremity.

Keywords: balloon angioplasty; brachytherapy balloon; critical limb ischemia; cryoplasty; cutting balloon; drug-eluting balloon; lower extremity intervention; percutaneous transluminal angioplasty; restenosis.

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Conflict of interest statement

Conflict of Interest Disclosure: All authors have completed and submitted the Methodist DeBakey Cardiovascular Journal Conflict of Interest Statement and none were reported.

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