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Multicenter Study
. 2013 Nov-Dec;46(6):702-6.
doi: 10.1016/j.jelectrocard.2013.05.006. Epub 2013 Jun 24.

Reference ranges of PR duration and P-wave indices in individuals free of cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis (MESA)

Elsayed Z Soliman  1 , Alvaro Alonso, Jeffrey R Misialek, Aditya Jain, Karol E Watson, Donald M Lloyd-Jones, Joao Lima, Steven Shea, Gregory L Burke, Susan R Heckbert
Affiliations
Multicenter Study

Reference ranges of PR duration and P-wave indices in individuals free of cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis (MESA)

Elsayed Z Soliman et al. J Electrocardiol. 2013 Nov-Dec.

Abstract

In this brief report, we provide normal reference ranges for PR duration [unadjusted and heart rate adjusted] and P-wave indices [duration, amplitude and terminal force in V1] in individuals free of cardiovascular disease and its risk factors. We used automatically processed digital ECG data from 1252 US participants [mean age 59 (± 10) years, 738 women, 588 whites, 207 African-Americans, 217 Hispanics, 240 Chinese] from the Multi-Ethnic Study of Atherosclerosis [MESA]. In multivariable adjusted linear regression models with PR and each P-wave variable as a separate outcome, significant age, sex and race differences in these markers were observed. Subsequently, we report reference ranges for abnormal [2nd and 98th percentiles], borderline abnormal [5th and 95th percentiles] and mean [SD] values of PR and P-wave indices stratified by age [middle age (45-64 years) and seniors (65-84 years)], sex [men and women] and race [whites, African Americans, Hispanics and Chinese].

Keywords: MESA; P-wave indices; PR interval.

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Conflict of interest statement

Competing interests: None

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