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Comment
. 2013 Jun 24;25(6):553-4.
doi: 10.1016/j.devcel.2013.06.009.

Argonaute regulation: two roads to the same destination

Judith Hauptmann  1 , Gunter Meister
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Argonaute regulation: two roads to the same destination

Judith Hauptmann et al. Dev Cell. .
Free article

Abstract

Reporting recently in Nature and Nature Structural and Molecular Biology, Shen et al. (2013) and Smibert et al. (2013) uncover mechanisms for Argonaute (Ago) protein regulation. Smibert et al. find that microRNA availability controls Ago levels, and Shen et al. show that epidermal growth factor receptor-mediated Ago2 phosphorylation affects Ago loading.

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