Instant recall: a key role for effector-phenotype CD8⁺ memory T cells in immune protection
- PMID: 23809159
- DOI: 10.1016/j.immuni.2013.06.007
Instant recall: a key role for effector-phenotype CD8⁺ memory T cells in immune protection
Abstract
In this issue of Immunity, Olson et al. (2013) demonstrate that circulating CD8⁺ memory T cells with an effector-like phenotype, previously thought to be mostly senescent, provide robust protection from a secondary pathogen challenge despite their poor secondary proliferative response.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Effector-like CD8⁺ T cells in the memory population mediate potent protective immunity.Immunity. 2013 Jun 27;38(6):1250-60. doi: 10.1016/j.immuni.2013.05.009. Epub 2013 Jun 6. Immunity. 2013. PMID: 23746652 Free PMC article.
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