Et Tu PDE2?

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Editorial

David A Kass. J Am Coll Cardiol. 2013.

Free article

. 2013 Oct 22;62(17):1607-9.

doi: 10.1016/j.jacc.2013.06.003. Epub 2013 Jun 26.

¹ Division of Cardiology, The Johns Hopkins Medical Institutions, Baltimore, Maryland. Electronic address: dkass@jhmi.edu.

No abstract available

Keywords: beta-adrenoceptor signaling; cAMP; cGMP; heart failure; phosphodiesterase 2.

Comment on

Phosphodiesterase-2 is up-regulated in human failing hearts and blunts β-adrenergic responses in cardiomyocytes.
Mehel H, Emons J, Vettel C, Wittköpper K, Seppelt D, Dewenter M, Lutz S, Sossalla S, Maier LS, Lechêne P, Leroy J, Lefebvre F, Varin A, Eschenhagen T, Nattel S, Dobrev D, Zimmermann WH, Nikolaev VO, Vandecasteele G, Fischmeister R, El-Armouche A. Mehel H, et al. J Am Coll Cardiol. 2013 Oct 22;62(17):1596-606. doi: 10.1016/j.jacc.2013.05.057. Epub 2013 Jun 26. J Am Coll Cardiol. 2013. PMID: 23810893