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. 2013 Jun 28;340(6140):1529-30.
doi: 10.1126/science.1240514.

Neuroscience. Garbage truck of the brain

Affiliations

Neuroscience. Garbage truck of the brain

Maiken Nedergaard. Science. .

Abstract

An intercellular “glymphatic” pathway clears cell waste from the brain and may reveal new targets for treating neurodegenerative diseases.

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Figures

Figure 1
Figure 1. Go with the flow
Convective glymphatic fluxes of CSF and ISF propel the waste products of neuron metabolism into the paravenous space, from which they are directed into lymphatic vessels and ultimately return to the general circulation for clearance by the kidney and liver.

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