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Editorial
. 2013 Nov;58(5):1526-8.
doi: 10.1002/hep.26596. Epub 2013 Sep 13.

Build a better mouse model, and the world will beat a path to your door

Affiliations
Editorial

Build a better mouse model, and the world will beat a path to your door

Gavin E Arteel. Hepatology. 2013 Nov.
No abstract available

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Figures

Fig. 1
Fig. 1
Schematic depiction of the NIAAA model. Ethanol or isocaloric maltose dextrin (control) liquid diet is fed ad libitum for 10 days. Mice are subsequently administered a bolus gavage of ethanol or isocaloric maltose-dextrin. Liver injury caused by ethanol diet or ethanol gavage alone is relatively minor and consists predominantly of steatosis. The combination of ethanol diet and ethanol gavage synergistically damages the liver, with active steatohepatitis. See Bertola et al. for methodological details.

Comment on

References

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