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Practice Guideline
. 2013 Jul;128(4):247-343.
doi: 10.1177/003335491312800403.

PHS guideline for reducing human immunodeficiency virus, hepatitis B virus, and hepatitis C virus transmission through organ transplantation

Debbie L Seem  1 , Ingi Lee, Craig A Umscheid, Matthew J Kuehnert; United States Public Health Service
Affiliations
Practice Guideline

PHS guideline for reducing human immunodeficiency virus, hepatitis B virus, and hepatitis C virus transmission through organ transplantation

Debbie L Seem et al. Public Health Rep. 2013 Jul.
No abstract available

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Figures

Figure 1
Figure 1
Major topic areas and key questions for the systematic literature review concerning HIV, HBV, and HCV transmission through organ transplantation
Figure 2
Figure 2
Major topic area and questions addressed by expert opinion relevant to HIV, HBV, and HCV transmission through organ transplantation
Figure 3
Figure 3
Categorization scheme applied to the 34 recommendations concerning HIV, HBV, and HCV transmission through organ transplantation
Figure 4
Figure 4
Deceased potential organ donor test recommendations based on risk status for HIV, HBV, and HCV infection
Figure 5
Figure 5
Living potential organ donor test recommendations based on risk status for HIV, HBV, and HCV infection
Figure 6
Figure 6
Pre- and posttransplant recipient test recommendations when a donor is at increased risk for HIV, HBV, or HCV infection; the donor's risk for HIV, HBV, and HCV infection is unknown; or the donor is infected with HCV or HBVa
Figure 7
Figure 7
HIV, HBV, and HCV tests used for organ donor screeninga
Figure 7
Figure 7
HIV, HBV, and HCV tests used for organ donor screeninga
Figure 8
Figure 8
Evidence-based process used to develop guideline recommendations for reducing HIV, HBV, and HCV transmission through organ transplantation
Figure 9
Figure 9
Analytical framework depicting the relationships among donor characteristics, organ availability, patient interventions, and subsequent outcomesa
Figure 10
Figure 10
Question-specific inclusion criteria applied during the systematic review of the literature regarding HIV, HBV, and HCV transmission through organ transplantation
Figure 11
Figure 11
Results of the study selection process to identify articles meeting inclusion criteria for the 10 key questions about HIV, HBV, and HCV transmission through donated organsa
Figure 12
Figure 12
Criteria used to assess data quality of each selected study for key questions regarding HIV, HBV, and HCV transmission through organ transplantationa
Figure 12
Figure 12
Criteria used to assess data quality of each selected study for key questions regarding HIV, HBV, and HCV transmission through organ transplantationa
Figure 13
Figure 13
Process for rating the quality of evidence for each outcome of interest concerning HIV, HBV, and HCV transmission through organ transplantation
Figure 14
Figure 14
Behavioral and nonbehavioral characteristics associated with HIV, HBV, or HCV identified by low- to high-quality evidence from a systematic review of the literature regarding the risks of transmitting HIV, HBV, and HCV through organ transplantation
See this image and copyright information in PMC

References

    1. Rogers MF, Simonds RJ, Lawton KE, Moseley RR, Jones WK. Guidelines for preventing transmission of human immunodeficiency virus through transplantation of human tissue and organs. MMWR Recomm Rep. 1994;43(RR-8):1–17. - PubMed
    1. Food and Drug Administration (US) Guidance for industry: eligibility determination for donors of human cells, tissues, and cellular and tissue-based products. 2007. Aug, [cited 2013 Mar 13]. Available from: URL: http://www.fda.gov/downloads/BiologicsBloodVaccines/GuidanceComplianceRe.... - PubMed
    1. Wolf JL, Perkins HA, Schreeder MT, Vincenti F. The transplanted kidney as a source of hepatitis B infection. Ann Intern Med. 1979;91:412–3. - PubMed
    1. Human immunodeficiency virus infection transmitted from an organ donor screened for HIV antibody—North Carolina. MMWR Morb Mortal Wkly Rep. 1987;36(20):306–8. - PubMed
    1. Bowen PA, 2nd, Lobel SA, Caruana RJ, Leffell MS, House MA, Rissing JP, et al. Transmission of human immunodeficiency virus (HIV) by transplantation: clinical aspects and time course analysis of viral antigenemia and antibody production. Ann Intern Med. 1988;108:46–8. - PubMed

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