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. 2013 Jul;26(3):290-2.
doi: 10.1080/08998280.2013.11928987.

Pulmonary tumor embolism syndrome from occult colonic adenocarcinoma

Affiliations

Pulmonary tumor embolism syndrome from occult colonic adenocarcinoma

Robert Evans Heithaus Jr et al. Proc (Bayl Univ Med Cent). 2013 Jul.

Abstract

Pulmonary tumor embolism syndrome is a rare phenomenon that can occur in patients who have an occult neoplasm that metastasizes. We describe a case of an elderly woman with an undiagnosed colon cancer who suffered from respiratory distress and compromised pulmonary blood flow from micrometastasis in the pulmonary arteries.

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Figures

Figure 1.
Figure 1.
Gross examination of the cecum revealed a several-centimeter tumor extending intraluminally. A cut through the center of the tumor (arrow) demonstrates the transmural thickness (double arrow).
Figure 2.
Figure 2.
Microscopic examination of the tumor revealed anaplastic cells with glands consistent with poorly differentiated adenocarcinoma (hematoxylin and eosin stain, 100×).
Figure 3.
Figure 3.
Sections of the pulmonary arteries revealed intravascular collections of fibrin and markedly anaplastic tumor cells consistent with poorly differentiated adenocarcinoma (hematoxylin and eosin stain, 100×).

References

    1. Roberts KE, Hamele-Bena D, Saqi A, Stein CA, Cole RP. Pulmonary tumor embolism: a review of the literature. Am J Med. 2003;115(3):228–232. - PubMed
    1. Kane RD, Hawkins HK, Miller JA, Noce PS. Microscopic pulmonary tumor emboli associated with dyspnea. Cancer. 1975;36(4):1473–1482. - PubMed
    1. Winterbauer RH, Elfenbein IB, Ball WC., Jr Incidence and clinical significance of tumor embolization to the lungs. Am J Med. 1968;45(2):271–290. - PubMed
    1. Keenan NG, Nicholson AG, Oldershaw PJ. Fatal acute pulmonary hypertension caused by pulmonary tumour thrombotic microangiopathy. Int J Cardiol. 2008;124(1):e11–e13. - PubMed
    1. Abbondanzo SL, Klappenbach RS, Tsou E. Tumor cell embolism to pulmonary alveolar capillaries. Cause of sudden cor pulmonale. Arch Pathol Lab Med. 1986;110(12):1197–1198. - PubMed