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. 2013 Jun;74(6):269-73.
doi: 10.4046/trd.2013.74.6.269. Epub 2013 Jun 25.

A case of isolated pulmonary mucormycosis in an immunocompetent host

Jung Su Lee  1 , Ho Cheol Kim, Sang Woo Park, Hoon Sub So, Chang Yun Woo, Jong Han Choi, Sang Hyung Kim, Se Jin Kim, Yeon-Mok Oh
Affiliations

A case of isolated pulmonary mucormycosis in an immunocompetent host

Jung Su Lee et al. Tuberc Respir Dis (Seoul). 2013 Jun.

Abstract

Mucormycosis is a rare fungal disease that holds a fatal opportunistic fungal infection in diabetes mellitus, hematological malignancy, and immunocompromised host. Isolated pulmonary mucormycosis is extremely rare. Optimal therapy is a combined medical-surgical approach and a management of the patient's underlying disease. Herein, we report a case-study of isolated pulmonary mucormycosis which was being presented as multiple lung nodules in a patient with no underlying risk factors. Considering that the patient had poor pulmonary functions, we treated him with only antifungal agent rather than a combined medical-surgical approach. After treatment with antifungal agent for six months, the nodules of pulmonary mucormycosis were improved with the prominent reductions of size on the computed tomography.

Keywords: Immunocompetence; Lung; Mucormycosis; Posaconazole.

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Figures

Figure 1
Figure 1
Initial chest radiography revealed two lung nodules in lower left lung field.
Figure 2
Figure 2
Computed tomography of chest showed three long nodules in lower left lobe of lung and one lung nodule in lower right lobe.
Figure 3
Figure 3
Pathological findings of lung tissue are shown as thick, irregular and non-septated fungal hyphaes with right-angle branching in hematoxylin and eosin stain (A, ×400) and Gomori's methenamine silver stain (B, ×400).
Figure 4
Figure 4
After treatment with antifungal agent for 3 months, computed tomography of chest showed the prominent reduction of size in the nodules of pulmonary mucormycosis.
Figure 5
Figure 5
After the end of the treatment for 3 months, chest radiography revealed no definitive relapse of mucormycosis.
See this image and copyright information in PMC

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