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. 2012 May;2(3):199-204.
doi: 10.2217/dmt.12.15.

Personalized medicine in Type 2 diabetes: what does the future hold?

Richard W Grant  1 , Deborah J Wexler
Affiliations

Personalized medicine in Type 2 diabetes: what does the future hold?

Richard W Grant et al. Diabetes Manag (Lond). 2012 May.

Abstract

The management of patients with Type 2 diabetes is based on a remarkably robust evidence base. Large clinical trials and lengthy observational cohort studies have clearly established the importance of glycemic, blood pressure and lipid level control. Indeed, most elements of guideline-based diabetes care can be supported by clinical research evidence. While such studies are critical for establishing treatment recommendations, the evidence derived from clinical trial participants applies to populations of patients rather than to the individual sitting before the clinician. An important next step in diabetes care would be to develop and implement a framework for personalizing care. In this article, we highlight the major reasons for personalization and discuss what the future of personalized diabetes care may hold.

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References

    1. Hamburg MA, Collins FS. The path to personalized medicine. N. Engl. J. Med. 2010;363(4):301–304. ▪ Opinion piece from national leaders focused on the potential for genomic medicine to support personalized care.

    1. Meigs JB, Shrader P, Sullivan LM, et al. Genotype score in addition to common risk factors for prediction of Type 2 diabetes. N. Engl. J. Med. 2008;359(21):2208–2219. - PMC - PubMed
    1. Standards of medical care in diabetes – 2011. Diabetes Care. 2011;34(Suppl. 1):S11–S61. - PMC - PubMed
    1. Nathan DM, Buse JB, Davidson MB, et al. Medical management of hyperglycemia in Type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care. 2009;32(1):193–203. - PMC - PubMed
    1. Hoerger TJ, Zhang P, Segel JE, Gregg EW, Narayan KM, Hicks KA. Improvements in risk factor control among persons with diabetes in the United States: evidence and implications for remaining life expectancy. Diabetes Res. Clin. Pract. 2009;86(3):225–232. - PubMed

Websites

    1. [Accessed 19 December 2011];NCQA Diabetes Recognition Program. www.ncqa.org/tabid/139/Default.aspx.
    1. Centers for Disease Control [Accessed 19 December 2011];National Diabetes Fact Sheet. 2011 www.cdc.gov/diabetes/pubs/factsheet11.htm.

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