Influence of miRNA-155 on lymphoma

Abstract

Lymphomas are the most common ones of hematologic tumors. In China, Hodgkin's lymphoma accounts for 9% - 10% of lymphomas, which has a good response to chemotherapy, while non-Hodgkin's lymphoma accounts for nearly 90% of lymphomas, and the incidence of which tends to rise in recent years. At present, it was realized that miRNA and lymphomas are closely related to each other. More attention has been paid to the effects of miRNA on the pathophysiological process of lymphoma. This review is focused on miRNA-155, one of the miRNA family members, and its action mechanism in diffuse large B-cell lymphoma, Burkitt lymphoma and Hodgkin's lymphoma, expecting to shed light on the future therapy.