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Case Reports
. 2013:7:1193-5.
doi: 10.2147/OPTH.S46792. Epub 2013 Jun 17.

Vancomycin-resistant Staphylococcus hominis endophthalmitis following cataract surgery

Affiliations
Case Reports

Vancomycin-resistant Staphylococcus hominis endophthalmitis following cataract surgery

Jun Yeon Won et al. Clin Ophthalmol. 2013.

Abstract

We report a case of acute postoperative endophthalmitis caused by vancomycin-resistant Staphylococcus hominis, treated at our hospital. An 80-year-old male presented 2 days after uncomplicated phacoemulsification and posterior chamber intraocular lens implantation, with a 24-hour history of progressive visual loss and redness in the operated (right) eye. On examination, best corrected visual acuity was counting fingers. Anterior segment examination revealed conjunctival injection, chemosis, corneal edema, and hypopyon. B-scan ultrasonography showed vitreous opacification, but no retinal detachment. Acute postoperative endophthalmitis was diagnosed. We performed vitrectomy with vancomycin in the irrigating solution, intraocular lens removal, and silicone oil tamponade. Culture of the vitreous grew Staphylococcus hominis. Antibiotic susceptibility testing showed the isolate was sensitive to trimethoprim/sulfamethoxazole and teicoplanin but resistant to ciprofloxacin, moxifloxacin, levofloxacin, cefazolin, and vancomycin. At 3 months, the visual acuity of the silicone oil-treated eye was 20/400.

Keywords: Staphylococcus hominis; endophthalmitis; vancomycin.

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Figures

Figure 1
Figure 1
B-scan ultrasonography demonstrated vitreous opacities but no retinal detachment.

References

    1. Jager RD, Aiello LP, Patel SC, Cunningham ET., Jr Risks of intravitreous injection: a comprehensive review. Retina. 2004;24(5):676–698. - PubMed
    1. Kloos WE, George CG, Olgiate JS, et al. Staphylococcus hominis subsp. novobiosepticus subsp. nov, a novel trehalose- and N-acetyl-D-glucosamine-negative, novobiocin- and multiple-antibiotic-resistant subspecies isolated from human blood cultures. Int J Syst Bacteriol. 1998;48(Pt 3):799–812. - PubMed
    1. Fitzgibbon JE, Nahvi MD, Dubin DT, John JF., Jr A sequence variant of Staphylococcus hominis with a high prevalence of oxacillin and fluoroquinolone resistance. Res Microbiol. 2001;152(9):805–810. - PubMed
    1. Palazzo IC, d’Azevedo PA, Secchi C, Pignatari AC, Darini AL. Staphylococcus hominis subsp. novobiosepticus strains causing nosocomial bloodstream infection in Brazil. J Antimicrob Chemother. 2008;62(6):1222–1226. - PubMed
    1. Iyer MN, Wirostko WJ, Kim SH, Simons KB. Staphylococcus hominis endophthalmitis associated with a capsular hypopyon. Am J Ophthalmol. 2005;139(5):930–932. - PubMed

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