Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jun 17:6:205-14.
doi: 10.2147/JMDH.S31659. Print 2013.

Vertebral compression fractures: a review of current management and multimodal therapy

Affiliations

Vertebral compression fractures: a review of current management and multimodal therapy

Cyrus C Wong et al. J Multidiscip Healthc. .

Abstract

Vertebral compression fractures are a prevalent disease affecting osteoporotic patients. When symptomatic, they cause significant pain and loss of function and have a high public health impact. In this paper we outline the diagnosis and management of these patients, with evidence-based review of treatment outcomes for the various therapeutic options. Diagnosis involves a clinical history focusing on the nature of the patient's pain as well as various imaging studies. Management is multimodal in nature and starts with conservative therapy consisting of analgesic medication, medication for osteoporosis, physical therapy, and bracing. Patients who are refractory to conservative management may be candidates for vertebral augmentation through either vertebroplasty or kyphoplasty.

Keywords: bracing; kyphoplasty; osteoporosis; vertebral compression fractures; vertebroplasty.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Lateral radiograph demonstrates biconcave-appearing compression fractures at L2 and L3, showing progression in loss of height in these X-rays taken a year apart.
Figure 2
Figure 2
Sagittal T2 magnetic resonance imaging demonstrating a traumatic burst fracture at L4 with bony retropulsion and canal compromise requiring open surgical decompression and fixation. Note: A concomitant acute compression fracture at L1 (note the bony edema) was treated with kyphoplasty in the same surgery.
Figure 3
Figure 3
Nuclear medicine bone scan demonstrating increased uptake at a T7 fracture.
Figure 4
Figure 4
Intraoperative images showing lateral and anteroposterior fluoroscopic images, after the injection of polymethylmethacrylate.
Figure 5
Figure 5
Pre- and postoperative X-rays demonstrating the restoration of vertebral body height after kyphoplasty.

References

    1. Ensrud KE, Schousboe JT. Clinical practice. Vertebral fractures. N Engl J Med. 2011;364(17):1634–1642. - PubMed
    1. Fink HA, Milavetz DL, Palermo L, et al. What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa? J Bone Miner Res. 2005;20(7):1216–1222. - PubMed
    1. Francis RM, Baillie SP, Chuck AJ, et al. Acute and long-term management of patients with vertebral fractures. QJM. 2004;97(2):63–74. - PubMed
    1. Cooper C. Epidemiology and public health impact of osteoporosis. Baillieres Clin Rheumatol. 1993;7(3):459–477. - PubMed
    1. Cauley JA, Palermo L, Vogt M, et al. Prevalent vertebral fractures in black women and white women. J Bone Miner Res. 2008;23(9):1458–1467. - PMC - PubMed