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. 1990 May;45(5):401-2.
doi: 10.1136/thx.45.5.401.

Concentrations of cefixime in bronchial mucosa and sputum after three oral multiple dose regimens

D R Baldwin  1 , J M Andrews, J P Ashby, R Wise, D Honeybourne
Affiliations

Concentrations of cefixime in bronchial mucosa and sputum after three oral multiple dose regimens

D R Baldwin et al. Thorax. 1990 May.

Abstract

In a study of 58 patients the concentrations of cefixime, a new oral cephem antibiotic, in bronchial mucosa were 35-40% of the concentrations found in simultaneously collected serum samples. The antibiotic was often undetectable in sputum despite a highly sensitive assay.

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References

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