Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jul;20(7):776-80.
doi: 10.1038/nsmb.2605.

SIMIBI twins in protein targeting and localization

Gert Bange  1 , Irmgard Sinning
Affiliations

SIMIBI twins in protein targeting and localization

Gert Bange et al. Nat Struct Mol Biol. 2013 Jul.

Abstract

Signal recognition particle, MinD and BioD (SIMIBI)-type nucleoside triphosphate-binding proteins are an ancient subfamily of nucleotide-binding proteins that serve in a wide range of cellular processes. Notably, this class comprises dimeric ATPases as well as GTPases (SIMIBI 'twins') and a subset of SIMIBI-type proteins, including SRP GTPases, MinD-type ATPases and the Get3 ATPase, is essential to protein targeting and localization. Here, we define common mechanistic principles and differences for these SIMIBI proteins.

PubMed Disclaimer

References

    1. Nature. 2009 Sep 17;461(7262):361-6 - PubMed
    1. Curr Opin Microbiol. 2011 Dec;14(6):726-33 - PubMed
    1. Annu Rev Biochem. 2011;80:943-71 - PubMed
    1. Nature. 1997 Jan 23;385(6614):365-8 - PubMed
    1. Nature. 1996 May 16;381(6579):248-51 - PubMed

Publication types

MeSH terms

LinkOut - more resources