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Case Reports
. 2013 Nov;45(11):885-7.
doi: 10.3109/00365548.2013.805426. Epub 2013 Jul 5.

Severe bone marrow suppression and hepatic dysfunction caused by piperacillin/tazobactam

Zhong-Fang He  1 , Xin-An Wu, Yan-Ping Wang
Affiliations
Case Reports

Severe bone marrow suppression and hepatic dysfunction caused by piperacillin/tazobactam

Zhong-Fang He et al. Scand J Infect Dis. 2013 Nov.

Abstract

Piperacillin/tazobactam (TZP) is a commonly prescribed antibiotic. Here, we report a patient who developed agranulocytosis, thrombocytopenia, and severe hepatic dysfunction on day 17 while receiving TZP treatment for an intracranial infection. Bone marrow suppression and hepatic dysfunction are serious adverse effects that should be kept in mind when using long-term TZP.

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