Introduction to autoinflammatory syndromes and diseases

Abstract

Autoinflammatory syndromes and diseases are a group of disorders of innate immunity. This group has grown rapidly in recent years as a result of research advancements in molecular biology and genetics. These diseases often present with skin manifestations and the dermatologist may not recognize the constellation of symptoms and medical history as a systemic inflammatory disease. Dermatologists would benefit from a deeper understanding of these diseases and the new treatments available for them.

Keywords: Autoinflammation; Familial Mediterranean fever; Inflammasome; Interleukins; Recurrent fever.