Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Apr;95(3):192-5.
doi: 10.1308/003588413X13511609958091.

Using therapeutic mammoplasty to extend the role of breast-conserving surgery in women with larger or ptotic breasts

Affiliations

Using therapeutic mammoplasty to extend the role of breast-conserving surgery in women with larger or ptotic breasts

A Currie et al. Ann R Coll Surg Engl. 2013 Apr.

Abstract

Introduction: The equivalence of breast-conserving surgery followed by postoperative radiotherapy against mastectomy is now firmly established in patients with early breast cancer. The results of surgery in large-breasted women can be poor, with radiation-induced fibrosis, chronic pain and poor cosmesis contributing to long-term psychological and physical morbidity. Therapeutic mammoplasty offers an alternative management strategy to both enhance the role of breast-conserving surgery and provide better outcomes.

Methods: A retrospective note review was undertaken of all patients undergoing therapeutic mammoplasty for breast malignancy between 2007 and 2011. All cases were performed using a Wise pattern-reduction technique. Histology and pathological outcomes were assessed. Postoperative outcomes reviewed included wound infection, seroma and need for further intervention.

Results: During the study period, 20 patients underwent therapeutic mammoplasty with a mean follow-up duration of 36 months. The mean weight of the lumpectomy specimen was 330g. The average cancer size was 34mm, with a mean margin clearance of 7mm. There was one episode of wound infection and three of delayed wound healing at the T-junction. One patient required a mastectomy for involved margins. There were no recurrences at the most recent follow-up visit.

Conclusions: Therapeutic mammoplasty offers a tailored approach to women with larger breasts and early breast cancers with good cosmetic results and oncological outcomes.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Example operative approach demonstrating technique. Cancer excised in reduction pattern excision on affected side with mirror reduction pattern excision of contralateral breast. Top: preoperative incision marking (dotted line) and example tumour location (star); middle: de-epithelialised pedicle flap (tinted area) with skin flaps closed over defect; bottom: postoperative wound closure and suture lines
Figure 2
Figure 2
Preoperative photograph of patient with 8cm right upper outer quadrant tumour undergoing therapeutic mammoplasty with preoperative markings
Figure 3
Figure 3
Postoperative photograph of patient at 1 year following therapeutic mammoplasty, radiotherapy and chemotherapy for 8cm right upper outer quadrant tumour

References

    1. Poggi MM, Danforth DN, Sciuto LCet al Eighteen-year results in the treatment of early breast carcinoma with mastectomy versus breast conservation therapy: the National Cancer Institute Randomized Trial. Cancer 2003; 98: 697–702. - PubMed
    1. Fisher B, Anderson S, Bryant Jet al Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 2002; 347: 1,233–1,241. - PubMed
    1. Fisher B, Costantino J, Redmond Cet al Lumpectomy compared with lumpectomy and radiation therapy for the treatment of intraductal breast cancer. N Engl J Med 1993; 328: 1,581–1,586. - PubMed
    1. Fitzal F, Mittlboeck M, Trischler Het al Breast-conserving therapy for centrally located breast cancer. Ann Surg 2008; 247: 470–476. - PubMed
    1. Poulsen B, Graversen HP, Beckmann J, Blichert-Toft M. A comparative study of post-operative psychosocial function in women with primary operable breast cancer randomized to breast conservation therapy or mastectomy. Eur J Surg Oncol 1997; 23: 327–334. - PubMed