Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2013 Sep;37(9):1027-34.
doi: 10.1016/j.leukres.2013.06.010. Epub 2013 Jul 1.

Early T-cell precursor leukemia/lymphoma in adults and children

Ashleigh Allen  1 , Anthony Sireci, Adrianna Colovai, Kerice Pinkney, Maria Sulis, Govind Bhagat, Bachir Alobeid
Affiliations
Comparative Study

Early T-cell precursor leukemia/lymphoma in adults and children

Ashleigh Allen et al. Leuk Res. 2013 Sep.

Abstract

Early T-cell precursor-ALL (ETP-ALL) is a subtype of T-ALL with a poor prognosis in children. We analyzed ETP-ALL compared to conventional T-ALL/LBL in both adults and children to determine any differences in clinical outcomes, based on the following parameters: induction failure, relapse, and survival. Patients with ETP-ALL have a higher risk of relapse, especially in children (in all patients, HR=4.08, p=0.127, and children, HR=11.63, p=0.025). ETP-ALL seems to have an increased risk of adverse outcomes, particularly in children. Larger studies are needed to better determine the prognosis of this subtype of T-ALL.

Keywords: ALL; Acute leukemia; Adults; Children; Early T-cell precursors; Leukemia; Lymphoblastic; Lymphoma; Prognosis.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources