Lessons from lipids in the fight against influenza
- PMID: 23827671
- DOI: 10.1016/j.cell.2013.06.024
Lessons from lipids in the fight against influenza
Abstract
Influenza is a leading cause of morbidity and mortality worldwide, with vaccines and antiviral drugs having limited efficacy thus far. Two recent studies in Cell apply lipidomics approaches to identify bioactive lipid mediators influencing host inflammation, viral replication, and disease progression.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza.Cell. 2013 Mar 28;153(1):112-25. doi: 10.1016/j.cell.2013.02.027. Epub 2013 Mar 7. Cell. 2013. PMID: 23477864
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Lipidomic profiling of influenza infection identifies mediators that induce and resolve inflammation.Cell. 2013 Jul 3;154(1):213-27. doi: 10.1016/j.cell.2013.05.052. Cell. 2013. PMID: 23827684 Free PMC article.
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