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Comment
. 2013 Jul 3;154(1):23-5.
doi: 10.1016/j.cell.2013.06.014.

Piecing together the extracellular puzzle

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Piecing together the extracellular puzzle

Daniel J Leahy. Cell. .
Free article

Abstract

Large-scale screens to identify protein interactions typically underperform with eukaryotic extracellular proteins. In this issue, Özkan et al. report development of a high-throughput assay designed specifically for extracellular proteins that uncovers a wealth of new interactions among three protein superfamilies in Drosophila and sets the stage for more extensive screens.

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