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. 2013 May-Jun;110(3):201-5.

A brief history of animal modeling

Affiliations

A brief history of animal modeling

Aaron C Ericsson et al. Mo Med. 2013 May-Jun.

Abstract

Comparative medicine is founded on the concept that other animal species share physiological, behavioral, or other characteristics with humans. Over 2,400 years ago it was recognized that by studying animals, we could learn much about ourselves. This technique has now developed to the point that animal models are employed in virtually all fields of biomedical research including, but not limited to, basic biology, immunology and infectious disease, oncology, and behavior.

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Figures

Figure 1
Figure 1
Pubmed search results by publication date, 1970 through 2011. Search terms for each species included the scientific name and the common name for each species; except that only the scientific name was used for mouse and rat. “Non-rodent mammalian models” includes the dog, rabbit, cat, rhesus macaque, guinea pig, swine, chimpanzee, and ferret.
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